Understanding CAS Number 139-07-1 A Comprehensive Overview
CAS Number 139-07-1 refers to a specific chemical substance known as Phenylhydrazine. This compound is characterized by its unique molecular structure and significant properties that make it an important entity in various scientific fields, including organic chemistry, analytical chemistry, and medicinal chemistry.
Phenylhydrazine is an organic compound with the molecular formula C6H8N2. It is primarily recognized for its role as a reagent in organic synthesis and its application in the determination of carbohydrates. The structure of Phenylhydrazine includes a phenyl group (a benzene ring) linked to a hydrazine group, characterized by the presence of two nitrogen atoms.
Properties of Phenylhydrazine
Phenylhydrazine appears as a yellow to red crystalline solid, often available in its hydrochloride form. It has a melting point of about 63-65 °C and is soluble in water, ethanol, and ether, which facilitates its use in various chemical reactions. However, it can be hazardous; it is known to be toxic and can cause skin and eye irritation. Consequently, proper safety measures are warranted when handling this compound in laboratory or industrial settings.
Applications of Phenylhydrazine
1. Synthesis of Hydrazones
One of the most notable applications of Phenylhydrazine is in the synthesis of hydrazones. These are compounds formed when Phenylhydrazine reacts with carbonyl compounds, such as aldehydes and ketones. The formation of hydrazones is an essential reaction in organic chemistry, serving as intermediates or derivatives that can further undergo various transformations. Hydrazones are increasingly used in the pharmaceutical industry to develop new drugs with therapeutic properties.
2. Detection of Carbohydrates
Phenylhydrazine is also noteworthy for its role in carbohydrate analysis. It forms a hydrazone with sugars, facilitating the identification and quantification of these vital biomolecules. The phenylhydrazone derivatives exhibit distinct melting points, which can be used as a characteristic property in distinguishing different types of sugars in a sample. This application is especially crucial in food chemistry and clinical diagnostics, as it assists in the analysis of dietary carbohydrates and blood sugar levels.
3. Research in Medical Fields
In medicinal chemistry, Phenylhydrazine has attracted attention due to its potential antitumor properties. Studies have shown that derivatives of Phenylhydrazine can exhibit cytotoxic activity against certain types of cancer cells. Research into these properties is ongoing, aiming to develop new anticancer agents that leverage the structural characteristics of Phenylhydrazine.
Safety and Handling
Given its toxicity, working with Phenylhydrazine requires stringent safety protocols. Laboratory personnel should wear appropriate personal protective equipment (PPE), including gloves, goggles, and lab coats. It is crucial to work in a well-ventilated area or fume hood to avoid inhalation of vapors or dust. In case of skin contact or ingestion, immediate medical attention should be sought, highlighting the importance of safety in chemical handling.
Conclusion
CAS Number 139-07-1, representing Phenylhydrazine, is more than just a numerical identifier; it encapsulates a compound rich in applications and significance within various scientific realms. Its unique properties make it a valuable reagent in organic synthesis, essential for carbohydrate detection and a promising candidate in pharmaceutical research. However, its toxicity necessitates careful handling and safety precautions. As research continues to evolve around Phenylhydrazine, its potential uses and benefits may expand further, reaffirming the critical role that such chemical compounds play in advancing science and medicine. Understanding these elements is essential for anyone working with or studying this important chemical.