High-Quality Isothiazolinones: Competitive Price & Versatile Uses

Isothiazolinones are a class of broad-spectrum biocides, renowned for their superior antimicrobial performance, safety, and versatility across industrial and consumer sectors. Major product types include 5-Chloro-2-methyl-4-isothiazolin-3-one (CMIT, CAS 26172-55-4) and 2-Methyl-4-isothiazolin-3-one (MIT, CAS 2682-20-4).

With the increased focus on sustainable manufacturing, regulatory compliance (e.g., REACH, ISO 9001), and performance optimization, the global isothiazolinones market was valued at $765.4 million USD in 2023, projected to grow at a CAGR of 5.2% through 2030 (Source: MarketsandMarkets).

Key related terms: chloro isothiazolinone (CMIT), isothiazolinone price fluctuations, product grades by CAS 2682-20-4 and CAS 26172-55-4, and isothiazolinone uses in water treatment, coatings, and metallurgy.

Figure 1: High-purity isothiazolinones (CMIT/MIT) for industrial water treatment — physical appearance.

Both CMIT and MIT display optimal activity against bacteria, fungi, and algae, making them essential in industrial water systems, paints & coatings, papermaking, and oilfield operations. Below is a comparative specifications table of major isothiazolinones product types:

• Raw materials: Acetone, thiourea, chlorine derivatives.
• Chemical synthesis: Controlled temperature (30-60°C), sequential chlorination and cyclization. Noteworthy for high-precision CNC blending for optimal pH and efficacy.
• Purification: Multi-step filtration (down to 0.22 microns), vacuum distillation to ensure high purity.
• Inspection standards: Adopts ISO 22241 testing, ANSI/NSF 60 potable water biocide validation, FDA protocols for residues & toxicity.
• Packing: Corrosion-resistant drums (HDPE/UN certified), batch tracking, full MSDS compliance.

Process control is enhanced with real-time PLC/SCADA monitoring and traceable batch records, offering industrial-grade consistency and reliability over a service life of 2–3 years in optimal storage.

The following section presents key technical trends, market pricing, and performance metrics of isothiazolinones using interactive charts for data-driven decision support.

• Raw Material Traceability: 100% feedstock trace from global certified suppliers (ISO 9001, REACH registration), ensuring product uniformity.
• Advanced Manufacturing Techniques: Processed via CNC metering blending, closed-loop additive control, and vacuum reaction, drastically reducing impurity content (
• Certification & Testing: Every batch undergoes ISO 22241 active ingredient testing; ANSI/NSF60 tested for potable water safety, and selected lots meet FDA CFR 21 for indirect food contact.
• Durability: Product stability validated under high/low temperature cycling, industry-typical shelf life ≥24 months in sealed drums.
• Environmental Compliance: VOC-free, biodegradable formulations available, lifecycle LCA evaluated for key markets.
• Anti-Corrosion, Anti-Foam: Specially engineered for minimal corrosion to system metals; foam suppression additives incorporated for closed-loop systems.

These technical strengths position Isothiazolinones (CMIT/MIT) as the preferred biocide for challenging industrial environments.

Source: Company websites, industry reports 2023

Isothiazolinones can be formulated to meet precise customer needs, with customization available for concentration (1.5%~14%), pH range, and specific additive technologies. Below are tailored solution scenarios:

• Petrochemical: Strong oxidizer resistance, prolonged anti-biofilm effect, certified for high-TDS brine systems.
• Metallurgy: High-temperature stable blends (up to 80°C), batch certified for process water microbiological control.
• Municipal Water: ANSI/NSF60 tested, ultra-low impurity grades for drinking water systems.
• Pulp & Paper Mills: Foam-inhibited, enhanced dispersibility to maximize wet-end process reliability.
• Paints & Coatings: Color-stability engineered; minimized impact on film formation, gloss retention tested (ASTM D523).
• Personal Care & Cosmetics: CAS 2682-20-4 pure MIT for hypoallergenic, low-sensitization preservation (compliant with EU/US limits).

Figure 2: Typical use — isothiazolinones dosing in industrial cooling water system pipelines.

Customer Feedback: LKP BTC's clients in the Middle East confirmed a 98.7% reduction in Legionella counts with CMIT/MIT versus 74% using non-isothiazolinone competitors (third-party certified, 2023). Other reported benefits include lower system corrosion, reduced biocide consumption, and improved regulatory inspection rates.

• Case 1: Oil Refineries, Asia – Switched from glutaraldehyde to CMIT/MIT 14% due to superior stabilization at pH 4–8, reducing annual biocide costs by 22% (Regulatory ref: GB 30962-2020).
• Case 2: Automotive Paint Shop, Europe – Adopted isothiazolinone blends eliminating 90% biofilm formation and reducing downtime, with no negative impact on gloss (validated per ASTM E2180).
• Case 3: Food Processing Plant, US – Switched to MIT (1.5%, CAS 2682-20-4) for non-rinse surface disinfection, achieving unmeasurable residuals post-cleaning (FDA LOD standard).

Our experienced tech team works closely with clients to design, trial, and validate customized chloro isothiazolinone solutions, ensuring regulatory and operational success.

• Order Lead Time: Typical production & shipment within 7–15 days for most grades.
• Warranty: 24-month shelf-life (factory-sealed, no direct UV), with stability data available upon request.
• Certifications: ISO 9001:2015, ISO 14001:2015, ANSI/NSF60 (NSF listing), RoHS compliance available.
• QA/QC: Batch-specific COA; microbial, pH, active content, and heavy metal tests per ISO/ASTM protocols.
• Support: Dedicated technical & regulatory experts, rapid TDS/MSDS dispatch, on-site training.
• Service Regions: Americas, EU, Middle East, SEA – local warehousing by arrangement.

Isothiazolinones (CMIT/MIT) set the gold standard for industrial biocides—backed by robust certifications, strict quality control, and proven application cases. By leveraging advanced process technology, strict ISO/ANSI/FDA compliance, and strong customer-centric support, Isothiazolinones continue to deliver exceptional value and operational reliability in water treatment, coatings, metallurgy, and beyond. For detailed TDS, free samples, or regulatory support, contact LKP BTC.