Dodecyl dimethyl benzyl ammonium chloride, also known as ADBAC, is a type of quaternary ammonium com

Benzalkonium chloride (BZK, BKC, BAK, BAC), also known as alkyldimethylbenzylammonium chloride (ADBAC) and by the trade name Zephiran, is a type of cationic surfactant. It is an organic salt classified as a quaternary ammonium compound. ADBACs have three main categories of use: as a biocide, a cationic surfactant, and a phase transfer agent.[2] ADBACs are a mixture of alkylbenzyldimethylammonium chlorides, in which the alkyl group has various even-numbered alkyl chain lengths.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep tightly closed. Keep this medicine in the original container. Throw away any unused medicine after the expiration date.NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Benzalkonium chloride (BAC) is a compound commonly used as a disinfectant and preservative in various products. It is an organic salt that exhibits strong antimicrobial properties, making it effective against a wide range of bacteria, viruses, and fungi.

Benzalkonium chloride is widely used in inhalations, IM injections, nasal, ophthalmic, and topical preparations as an antimicrobial preservative, antiseptic, disinfectant, solubilizing and wetting agent. It is used in similarly to other cationic surfactants, such as cetrimide.In ophthalmic preparations, benzalkonium chloride is the preservative of choice and one of the most widely used preservatives, at concentrations of 0.01-0.02% w/v.Antimicrobial activity can be enhanced, particularly against strains of Pseudomonas, benzalkonium chloride, through combination with other preservatives or excipients, such as 0.1% w/v Disodium edetate, phenylethanol or chlorhexidine.In nasal formulations, benzalkonium chloride is used at a concentration of 0.002-0.02% w/v. Levels of 0.01% w/v have also been utilized in small-volume parenteral products.

While the misuse of antibiotics has clearly contributed to the emergence and proliferation of resistant bacterial pathogens, with major health consequences, it remains less clear if the widespread use of disinfectants, such as benzalkonium chlorides (BAC), a different class of biocides than antibiotics, has contributed to this problem. Here, we provide evidence that exposure to BAC coselects for antibiotic-resistant bacteria and describe the underlying genetic mechanisms. After inoculation with river sediment, BAC-fed bioreactors selected for several bacterial taxa, including the opportunistic pathogen Pseudomonas aeruginosa, that were more resistant to several antibiotics than their counterparts in a control (no BAC) bioreactor. A metagenomic analysis of the bioreactor microbial communities, confirmed by gene cloning experiments with the derived isolates, suggested that integrative and conjugative elements encoding a BAC efflux pump together with antibiotic resistance genes were responsible for these results. Furthermore, the exposure of the P. aeruginosa isolates to increasing concentrations of BAC selected for mutations in pmrB (polymyxin resistance) and physiological adaptations that contributed to a higher tolerance to polymyxin B and other antibiotics. The physiological adaptations included the overexpression of mexCD-oprJ multidrug efflux pump genes when BAC was added in the growth medium at subinhibitory concentrations. Collectively, our results demonstrated that disinfectants promote antibiotic resistance via several mechanisms and highlight the need to remediate (degrade) disinfectants in nontarget environments to further restrain the spread of antibiotic-resistant bacteria.

When benzalkonium chloride comes into contact with the skin, it can cause irritant contact dermatitis or allergic contact dermatitis in some individuals.Benzalkonium chloride is a well-known irritant [1]. Irritant contact dermatitis due to benzalkonium chloride is more common than allergic contact dermatitis from its use.

Benzalkonium Chloride (BZK or BAC) is a widely used antiseptic and disinfectant. It is known by several trade names, including Zephiran, Bactine, and Dettol, depending on the formulation and market. As a quaternary ammonium compound, Benzalkonium Chloride is utilized in a variety of applications, from surface disinfection to active ingredients in personal care products. The compound targets bacterial cell membranes, making it highly effective against a broad spectrum of bacteria, viruses, and fungi.

Quaternary ammonium compounds (Quats) are membrane-active agents well known for their efficacy against bacteria, fungi, algae, and enveloped viruses. A popular example is Benzalkonium Chloride (BKC), an antiseptic ingredient often formulated in topical, ophthalmic, nasal and oral preparations.By deactivating viruses through the disruption of lipid membranes, BKC is effective against a long list of enveloped viruses, including enteroviruses, rotaviruses, norovirus, influenza virus, severe acute respiratory syndrome coronavirus (SARS-CoV), rhinovirus, chlamydia, herpes simplex and hepatitis A.

Benzalkonium chloride/benzocaine is a topical solution used to treat cold sores and fever blisters. Benzalkonium chloride/benzocaine is a combination of an antiseptic and a local anesthetic that work together to prevent infection and relieve pain temporarily. Common side effects of benzalkonium chloride/benzocaine include transient stinging sensation at the application site. Check with your physician before using benzalkonium chloride/benzocaine, if you are pregnant or breastfeeding.

Benzalkonium chlorides are a quaternary ammonium compound with two alkyl groups attached to a nitrogen atom. This makes it a cationic surfactant. Cationic surfactants are compounds that attract and hold negatively charged particles, such as bacteria, onto surfaces. They are commonly used in personal care products because they help prevent bacterial growth.This QAC-based formulation is effectively active against harmful viruses, bacteria, yeast, fungi, and other cationic surfactants. It has an important role in preventing the spread of pathogens.

Benzalkonium chloride (BAC) is a broad-spectrum quaternary ammonium compound biocide. The term relates to a chemical class with a dimethyl benzyl ammonium chloride structure and a variable length (C8 to 18) alkyl chain.BAC has a wide antimicrobial action against fungi, algae, bacteria, and viruses because of having long half-life and low toxicity. BAC is utilized at high concentrations (greater than 0.05 percent) in hospitals and households as surface disinfection and at lower doses(0.002 to 0.02 percent) as a preservative in medical formulations like eye drops and intranasal sprays.

Benzalkonium Chloride is a common ingredient in many cosmetic and personal care products due to its effectiveness as a cleansing agent, preservative, and surfactant. It has the chemical formula of C17H30ClN and is typically used in concentrations of 0.1% to 0.13%. As a surfactant, Benzalkonium Chloride helps to reduce surface tension and allows for easier spreading and mixing of cosmetic ingredients. Products with Benzalkonium Chloride can include cleansers, shampoos, conditioners, and other personal care items. However, some people may be sensitive to this ingredient and may experience skin irritation or other adverse reactions.

Use benzalkonium chloride/benzocaine with caution during pregnancy if the benefits outweigh the risks. Animal studies show risk and human studies are not available or neither animal nor human studies were done.It is unknown whether benzalkonium chloride/benzocaine is distributed in breast milk.Pregnant or breastfeeding patients should seek the advice of a health professional before using over-the-counter (OTC) drugs.

Benzalkonium chloride is a quaternary ammonium mixture of alkyl, dimethyl and benzyl ammonium chlorides.It is an irritant rather than a sensitizer, but may cause contact dermatitis in nursing and medical personnel. An unusual case was reported in a farm worker who used a detergent containing benzalkonium chloride to clean the piggery.

Benzalkonium Chloride qualifies as a broad-spectrum antimicrobial. It works by disrupting the membranes of microbes thus weakening and eventually killing them. Because the action of Benzalkonium Chloride kills microbes, the ingredient is called a Biocide. In cosmetic science we use ingredients like this as both actives (antimicrobials) and preservatives. In the case of preservatives, they can be microbiocidal (biocides) or micro biostatic with biocidal molecules generally being thought of as 'harsher', stronger or more effective. While biocidal preservatives are still used in cosmetics, there is a strong trend towards micro-biostatic technology as we learn more about topics such as antibiotic resistance, the skins microbiome and the environmental impacts of biocides.

Benzalkonium Chlorides (BACs) are a group of quaternary ammonium compounds widely used in personal care products.Benzalkonium Chloride (BAC) are a group of quaternary ammonium compounds widely used in various industry applications for their antimicrobial properties. Benzalkonium Chloride also serves as a powerful preservative, extending the shelf life of various products. BAC is particularly effective at preventing the growth of bacteria and fungi, which can cause products to spoil or become contaminated.This article explores Benzalkonium Chloride (BAC) uses, properties, sources, and applications across various personal care and cosmetic products — along with information regarding the regulatory environment governing its use in product development.

Tell the doctor and pharmacist about all of your child’s drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe to give this drug with all of your child’s other drugs and health problems. Do not start, stop, or change the dose of any drug your child takes without checking with the doctor.

People have become more aware of the importance of hand hygiene, boosting the use of antiseptic hand sanitizers with benzalkonium chloride, alcohol and other germ-fighting ingredients. Find out more about this ingredient in hand sanitizer. 

Benzalkonium chloride, also known as BZK or BAC, is a type of cationic surfactant that has been widely used for its antimicrobial properties. It is commonly found in disinfectants, antiseptics, and preservatives in various pharmaceutical and household products. The mechanism of benzalkonium chloride can be understood by examining its structure, mode of action, and applications.